A 45-year-old Florida man is recovering in intensive care after self-administering injections of his own sperm into his lower back, hoping to alleviate chronic pain—but instead triggering a life-threatening bacterial infection. The bizarre case, detailed in a New England Journal of Medicine*, has experts warning about the perils of unproven home remedies and the importance of evidence-based treatment.
According to the published report, the patient, identified only as “John Doe,” had suffered recurring lumbar pain for over a decade. Frustrated by limited relief from physical therapy and over-the-counter medications, he resorted to an online forum where users touted “biological injections” as a miracle cure. “I thought it was natural and harmless,” he later told CNN Health. “I never imagined I’d end up fighting for my life.”
@CDCgov “DIY injections pose serious risks—avoid unvalidated treatments and consult a medical professional.” CDC advisory tweet
Within 48 hours of his first shot, Doe experienced fever, chills, and excruciating pain radiating into his legs. He was admitted to a local hospital, where MRI scans revealed an epidural abscess compressing his spinal cord. Surgeons performed an emergency laminectomy to drain the pus, while infectious-disease specialists identified Staphylococcus aureus—a common skin bacterium—as the culprit, according to his attending physician, Dr. Maria Alvarez, in an interview with Reuters Health.
@ReutersHealth “Self-injected sperm led to spinal abscess—experts call for greater public awareness of injection dangers.” Reuters tweet
Dr. Alvarez emphasized that any substance not prepared under sterile, medical-grade conditions can introduce pathogens into deep tissues. “Injecting bodily fluids is never safe,” she told NBC News. “We saw rapid deterioration—if left untreated, he could have faced permanent paralysis or death.”

In response to the case, the FDA issued a consumer alert reminding the public that only licensed professionals should perform injections. “Home injections of unregulated substances can cause adverse events ranging from severe infection to embolism,” the statement read, as shared by @FDArecalls earlier today (FDA safety update).
The phenomenon of self-experimentation is not new—reports of people injecting herbs or vitamins date back decades—but experts say the ease of online misinformation has fueled a resurgence. “We’re seeing more DIY medical hacks trending on social media,” says Dr. Elena Rohde of the World Health Organization. “Platforms must do more to curb dangerous content.”
@WHO “Only use injections prescribed and administered by healthcare professionals. DIY medicine can be fatal.” WHO public health tweet
For his part, Doe called on others to avoid self-treatment: “I was desperate, but this isn’t the way. Please, talk to a doctor first.” He remains hospitalized on intravenous antibiotics and is undergoing rehabilitation to regain strength and mobility. His prognosis is cautiously optimistic, though he may require long-term pain management under medical supervision.
Clinical guidelines from the North American Spine Society recommend multimodal therapy—physical therapy, pharmacotherapy, and when necessary, interventional procedures performed by trained specialists. “Patients should never self-administer injections,” notes Dr. David Lin, an interventional pain physician quoted by Medscape News. “Even autologous platelet-rich plasma, which uses one’s own blood, must be prepared and injected under strict protocols.”

@Medscape “Case highlights critical need for regulated interventional pain services.” Medscape clinical tweet
Online, reactions have ranged from shock to regret. Under #LessonLearned, users like @ScienceMom23 warned, “No more weekend warrior procedures—leave injections to the professionals,” while some skeptics blamed sensationalized headlines for luring vulnerable patients into risky experiments.
@ScienceMom23 “This should be a wake-up call—DIY medicine is not a YouTube tutorial.” Parenting advice tweet
As Doe approaches discharge, his care team is coordinating with pain-management specialists to construct a safer, evidence-based plan incorporating physical therapy, nonsteroidal anti-inflammatory drugs, and cognitive-behavioral therapy. “Chronic pain can be managed effectively without risking your life,” says Dr. Rohde in a Psychology Today* article.
@PsychToday “Integrative pain strategies can reduce opioid and interventional risks.” Mental health insight tweet
This harrowing incident underscores a critical public-health message: no remedy found on the internet is a substitute for professional medical advice. As social-media platforms and health authorities scramble to issue warnings, Doe’s ordeal stands as a stark reminder—sometimes the cure can be as dangerous as the disease.